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Canadian Medical Association Journal, Vol 157, Issue 4 408-416, Copyright © 1997 by Canadian Medical Association


Review * Synthèse

Translating guidelines into practice: a systematic review of theoretic concepts, practical experience and research evidence in the adoption of clinical practice guidelines

D. A. Davis and A. Taylor-Vaisey

OBJECTIVE: To recommend effective strategies for implementing clinical practice guidelines (CPGs). DATA SOURCES: The Research and Development Resource Base in Continuing Medical Education, maintained by the University of Toronto, was searched, as was MEDLINE from January 1990 to June 1996, inclusive, with the use of the MeSH heading "practice guidelines" and relevant text words. STUDY SELECTION: Studies of CPG implementation strategies and reviews of such studies were selected. Randomized controlled trials and trials that objectively measured physicians' performance or health care outcomes were emphasized. DATA EXTRACTION: Articles were reviewed to determine the effect of various factors on the adoption of guidelines. DATA SYNTHESIS: The articles showed that CPG dissemination or implementation processes have mixed results. Variables that affect the adoption of guidelines include qualities of the guidelines, characteristics of the health care professional, characteristics of the practice setting, incentives, regulation and patient factors. Specific strategies fell into 2 categories: primary strategies involving mailing or publication of the actual guidelines and secondary interventional strategies to reinforce the guidelines. The interventions were shown to be weak (didactic, traditional continuing medical education and mailings), moderately effective (audit and feedback, especially concurrent, targeted to specific providers and delivered by peers or opinion leaders) and relatively strong (reminder systems, academic detailing and multiple interventions). CONCLUSIONS: The evidence shows serious deficiencies in the adoption of CPGs in practice. Future implementation strategies must overcome this failure through an understanding of the forces and variables influencing practice and through the use of methods that are practice- and community-based rather than didactic.


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BMJHome page
S. R Weingarten, J. M Henning, E. Badamgarav, K. Knight, V. Hasselblad, A. Gano Jr, and J. J Ofman
Interventions used in disease management programmes for patients with chronic illness---which ones work? Meta-analysis of published reports
BMJ, October 26, 2002; 325(7370): 925 - 925.
[Abstract] [Full Text] [PDF]


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BMJHome page
A. Kiessling and P. Henriksson
Efficacy of case method learning in general practice for secondary prevention in patients with coronary artery disease: randomised controlled study
BMJ, October 19, 2002; 325(7369): 877 - 880.
[Abstract] [Full Text] [PDF]


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JAMAHome page
P. E. Mazmanian and D. A. Davis
Continuing Medical Education and the Physician as a Learner: Guide to the Evidence
JAMA, September 4, 2002; 288(9): 1057 - 1060.
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Psychiatr. Serv.Home page
K. K. Milner and M. Valenstein
A Comparison of Guidelines for the Treatment of Schizophrenia
Psychiatr Serv, July 1, 2002; 53(7): 888 - 890.
[Abstract] [Full Text] [PDF]


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Evid. Based Nurs.Home page
C. Waddell
So much research evidence, so little dissemination and uptake: mixing the useful with the pleasing
Evid. Based Nurs., April 1, 2002; 5(2): 38 - 40.
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StrokeHome page
C. D. Bushnell and L. B. Goldstein
Physician Knowledge and Practices in the Evaluation of Coagulopathies in Stroke Patients
Stroke, April 1, 2002; 33(4): 948 - 953.
[Abstract] [Full Text] [PDF]


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ChestHome page
C. L. Kohler and W. C. Bailey
Tobacco Dependence : A Chronic Disease
Chest, March 1, 2002; 121(3): 686 - 687.
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Clin. Chem.Home page
C. van Walraven
Practice Guidelines and Practicing Physicians--Who's Guiding Whom?
Clin. Chem., January 1, 2002; 48(1): 9 - 10.
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Eur Respir JHome page
N. Roche, T. Lepage, J. Bourcereau, and P. Terrioux
Guidelines versus clinical practice in the treatment of chronic obstructive pulmonary disease
Eur. Respir. J., December 1, 2001; 18(6): 903 - 908.
[Abstract] [Full Text] [PDF]


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ChestHome page
D. M. Arnold, S. R. Kahn, and I. Shrier
Missed Opportunities for Prevention of Venous Thromboembolism : An Evaluation of the Use of Thromboprophylaxis Guidelines
Chest, December 1, 2001; 120(6): 1964 - 1971.
[Abstract] [Full Text] [PDF]


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Psychiatr. Serv.Home page
F. Azocar, B. D. Cuffel, W. Goldman, and J. McCulloch
Best Practices: Dissemination of Guidelines for the Treatment of Major Depression in a Managed Behavioral Health Care Network
Psychiatr Serv, August 1, 2001; 52(8): 1014 - 1016.
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Clin. Chem.Home page
M. J. McQueen
Overview of Evidence-based Medicine: Challenges for Evidence-based Laboratory Medicine
Clin. Chem., August 1, 2001; 47(8): 1536 - 1546.
[Abstract] [Full Text] [PDF]


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CMAJHome page
W. W. Rosser, D. Davis, and E. Gilbart
Promoting effective guideline use in Ontario
Can. Med. Assoc. J., July 1, 2001; 165(2): 181 - 182.
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PediatricsHome page
J. L. Lustig, E. M. Ozer, S. H. Adams, C. J. Wibbelsman, C. D. Fuster, R. W. Bonar, and C. E. Irwin Jr
Improving the Delivery of Adolescent Clinical Preventive Services Through Skills-Based Training
Pediatrics, May 1, 2001; 107(5): 1100 - 1107.
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CLIN PEDIATRHome page
J. J. Bazarian, T. Veenema, A. F. Brayer, and E. Lee
Knowledge of Concussion Guidelines Among Practitioners Caring for Children
Clinical Pediatrics, April 1, 2001; 40(4): 207 - 212.
[Abstract] [PDF]


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CMAJHome page
F. A. McAlister, N. R.C. Campbell, K. Zarnke, M. Levine, and I. D. Graham
The management of hypertension in Canada: a review of current guidelines, their shortcomings and implications for the future
Can. Med. Assoc. J., February 1, 2001; 164(4): 517 - 522.
[Abstract] [Full Text] [PDF]